Friday, 11 September 2020

Closed System Drug Transfer Device (CSTD) Market Size, Share, Report and Forecast

 Market Analysis 


The worldwide closed system drug transfer device (CSDT) market is projected to touch USD 6,312.52 million at a 19.10% CAGR between 2018-2025states the new Market Research Future (MRFR) report. A closed system drug transfer device simply put is a device which mechanically limits the outflow of vapor concentrations or hazardous drug outside the system at the time of the reconstitution and administration of the drug and the inflow of environmental contaminants. It allows the transfer of drugs sans, exposing the same to healthcare experts handling harmful drugs. In fact, it is extremely useful to transfer cytotoxic chemotherapeutic drugs and agents such as cancer-treating drug, antineoplastic. 


Numerous factors are adding to the growth of the global closed system drug transfer device market. These factors, according to the latest Market Research Future report, include rising incidence of cancer, rising use of CSTDs for combating harmful effects of antineoplastic or cytotoxic drugs, rising number of approvals of oncology drugs, and need to prevent chromosomal abnormalities among physicians and their staff. 


On the contrary, inadequate product efficiency, coupled with a lack of comprehensive guidelines, especially in emerging nations, are factors that may impede the global closed system drug transfer device market during the forecast period. 


Market Segmentation


The Market Research Future report provides a complete segmental analysis of the global closed system drug transfer device market based on end user, delivery, and type. 


By type, the global closed system drug transfer device market is segmented into barrier-type and filtration-type. Of these, the barrier-type segment will have the largest share in the market during the forecast period. 


By delivery, the global closed system drug transfer device market is segmented into closed syringe safety devices, closed vial access devices, and closed bag/line access devices. Of these, the closed bag/line access devices will dominate the market during the forecast period. 


By end users, the global closed system drug transfer device market is segmented into hospitals and clinics, specialty centres, and others (research & academic institutions and research laboratories). Of these, specialty centres will lead the market during the forecast period. 

 

 

Regional Analysis


By region, the global closed system drug transfer device market report covers the latest trends and growth opportunities across the Americas, Europe, the Asia Pacific, and the Middle East and Africa. Of these, the Americas will command the largest share in the market during the forecast period. Numerous factors are adding to the growth of the closed system drug transfer device market in the region such as the increasing prevalence of cancer, increasing funding support for encouraging R&D infrastructure, advances in technology in the healthcare sector, and increasing awareness about closed system drug transfer devices. Moreover, increasing geriatric population, huge patient pool in the region undergoing cancer treatments, increase in research activities, developed healthcare infrastructure, and presence of key market players in the region are also adding to the market growth. Canada and the US are the leading market players in the region for the increasing adoption of CSTDs. 


The worldwide closed system drug transfer device (CSDT) market in Europe will have healthy growth during the forecast period. Numerous factors are adding to the growth of the closed system drug transfer device market in the region, such as the presence of top pharma companies in the region, expanding life science industry, and flourishing medical device market. The region’s resurging economy plays a pivotal role in the growth of the market, enabling the expansion of the healthcare industry. Moreover, increasing investment in the development of a closed system drug transfer device is also adding to the market growth. 


The worldwide closed system drug transfer device (CSDT) market in the APAC region will develop at a quick pace during the forecast period for the various investments made by new market players, rising incidence of cancer, initiatives undertaken by the government for encouraging the practices of safe drug handling in China, and India, rapidly developing healthcare technology, and growing need for quality devices in biotechnology. 


The global closed system drug transfer device (CSDT) market in the MEA will have stable growth during the forecast period


Key Players 


Notable players profiled in the global closed system drug transfer device market report include Equashield LLC (US), ICU Medical Inc. (US), Yukon Medical (US), Corvida Medical (US), Dickinson and Company (US), Becton, and Teva Pharmaceutical Industries Ltd. (Israel). 


Industry News


October 2019: Leading CSTD (closed system transfer devices) provider Equashield will introduce its automated and manual CSTD solutions in Netherlands with the help of direct sales channels. 


January 2019: OnGuard CSTD from the renowned brand B. Braun has qualified as an efficient barrier for vapor release that is based on the NIOSH Draft Universal Protocol. 


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Latest Research : ​​​​​​​Clinical laboratory services Market Trends, Analysis, Global Forecast to 2025

 Clinical laboratory services Market-Overview

Clinical laboratory services are the services provided for research; it includes the examinations of the biochemistry, forensic science, foods and many more. The lab services also include the test on specimens from the human body. These tests usually include blood or urine; the analysis conducted in the lab is done to diagnose and treat the patients suffering from any disease.

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The clinical laboratory provides highly-reliable data to the doctor involved in the medical practises. These data determine the disease in the human body. There are various kinds of services provided by the laboratory services; it includes blood count, cholesterol tests, urinalysis, haemoglobin and many other diagnostics. The laboratory services always aim to improve the health status of the sample by providing the best quality of the service.

The rise of chronic diseases is one of the major factors that fuel the growth of laboratory services. The advance monitoring of the condition and the awareness about the diseases drives the global clinical laboratory service market. The market is expected to grow more with an increasing number of unknown diseases.

Key market segments of Clinical laboratory services 

The global clinical laboratory service market is segmented into types and application, further based on its kind the clinical laboratory service market is classified into many types. It includes genetic testing, microbiology, haematology, endocrinology, biochemistry histopathology and others. The biochemistry segments are expanding at a rapid pace. The increasing awareness and monitoring of the disease is the critical reason for the rise of biochemistry segment.

Based on the application, the global clinical laboratory market is divided into the independent laboratory, hospital laboratory and reference laboratory. The hospital laboratory is dominating the global market. The favourable reimbursement of the policies is one of the crucial reasons that drive the market. Most of the people prefer hospitals for any test, availability of various tests, and increasing volume of the patients makes hospital laboratory one of the growing segments in the global market. The hospital laboratory can boost up the global market to reach a value of USD 182,592 million by 2025.

Clinical laboratory services Market Regional overview

North America dominates the global market compared to all the regions. Large allocation of the healthcare expenditure accompanied by the expansion of the labs, reimbursement policies, and research on various drugs is critical reasons for the regional market growth.

Europe follows North America. Europe is the second region after North America that dominates the regional market. Policies enforced by reputed healthcare organizations for the prevention of chronic diseases are the primary factor that boosts the Regional growth of the laboratory clinical service market.

Recent industry news

The clinical laboratory service market is about to experience a boost in the global market. Advancements in the laboratory services will change the market scenario. The rise of chronic diseases and many unknown diseases will also fuel the comprehensive clinical laboratory services. The advancement in the services globally and the changes made by the market leaders will boost up the market till 2025.

Clinical laboratory services Market Companies Covered:

Laboratory Corporation of America Holdings, Mayo Medical Laboratories, Spectra Laboratories Inc, Unilabs, Bio-Reference Laboratories, Clinical Reference Laboratory, Adicon Clinical Laboratory, Amedes Holdings, Lifelabs Medicals Laboratories, Quest Diagnostics Incorporated, Synlab International, ACM Medical Laboratory, Eurofins Scientific, Cerba Healthcare and Sonic Healthcare.

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Regional Trends On cancer diagnostics market  Size, Share and Forecast

 The cancer diagnostics market is expected to be valued at USD 163,000 million by 2025 with a CAGR of 8.9% during the forecast period (2019-2025). Market Research Future (MRFR) made several revelations regarding factors that can improve the market’s growth patterns. 

These factors are growing technological advancement, better funding for research and development, hike in awareness level, various government initiatives to build the awareness level, and others. Hospitals and diagnostic centers are also triggering the demand for the same by providing better structural setup. However, its high cost and poor reimbursement schemes can hold back the cancer diagnostics market growth. 

Segmentation:

The global market for cancer diagnostics has been segmented on the basis of type, application, and end user. The report has valuable insights into these segments, which could be used later to develop advanced strategies and ensure a hike in profit margin. 

By type, the market for cancer diagnostics can be segmented into biomarkers testing, imaging testing, biopsy, in vitro diagnostic testing, and others. The imaging testing segment includes computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET). The biomarker testing relies on molecules secreted by a tumor or it tracks a specific response from various body parts to identify cancer. Imaging testing is mainly needed in the early stages to identify cancerous growth. Biopsy has substantial market growth as it is needed to be certain whether the tumor is cancerous or not. The process includes the removal of tissue from the area and a detailed analysis of it. The in-vitro diagnostics segment is also expected to fetch revenues substantially as it depends much on blood and tissue collection. 

By application, the market report contains segments like breast cancer, lung cancer, melanoma cancer, colorectal cancer, liver cancer, prostate cancer, and others. Breast cancer is more common in women but, in recent times, men are also getting diagnosed with it. The American Cancer Society identifies that in the US around 234,030 new lung cancer cases have been registered in 2018. Melanoma cancer is just 1% of all the skin cancer types but it is the deadliest. The colorectal cancer is the third most common cancer type in the US, as per the reports of cancer.org (skin cancer excluded). Liver cancer is more common in lesser developed countries. World Cancer Research Fund identifies that in 2018, 1.3 million new prostate cancer cases were registered. 

Regional Analysis:

The Americas would take the lead of the global cancer diagnostics market. Structural and financial benefits would simplify the integration of cancer diagnostics procedures. This is due to the presence of countries like the US and Canada where growth gets backed by research funding. In Europe, similar scenarios would help market growth. Better technologies and a hike in awareness are going to influence the market outcome. 

The Asia Pacific market would be the fastest-growing as the emerging countries are spending much to develop their healthcare sector. 

Competitive Analysis:

The global report on the cancer diagnostics market would include various companies like Arquer Diagnostics Ltd, Exact Sciences Corporation, Biotheranostics, Cancer Diagnostics, Inc., BioMark Diagnostics Inc., Thermo Fisher Scientific, Inc., Agilent Technologies, Inc., Becton, Dickinson and Company (BD), Illumina, Inc., Siemens Healthcare, QIAGEN N.V., GE Healthcare, Roche Diagnostics, Abbott Laboratories, Inc., and Koninklijke Philips N.V., Inc. 

Industry News:

In February 2020, researchers from the John Hopkins School of Medicine developed a new strategy where they used CRISPR-Cas9 gene-editing technology a nanowire sequencing technology to initiate better cancer diagnostic procedures. 

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Analysis on Blood Glucose Monitoring Market Forecast From 2018 to 2023

Overview

Blood glucose monitoring method is used for testing glucose levels in the blood. Due to the worldwide rise in diabetic patients, the market is showing significant growth. The global blood glucose monitoring market is expected to show about 07% annual growth rate. These monitoring devices help in early recognition of hypo and hyperglycaemic disorders. Due to unhealthy lifestyles, increased obese patients and lack of physical exercises are the main factors in the increase of diabetes. Hence increase in growth rate and overall market share.

Current market leaders are making continuous efforts to develop new methods and innovate next-level devices, which will not only help the market growth but also help the individual companies to come out as better market holders. Non-invasive techniques are the newest and most asked for procedures. Research for an introduction of new non-invasive methods is also helping the market to gain pace. On observing the increase in blood glucose-related disorders, authorities and socially active organisations are on a permanent run to look for better methods to decrease the severe health complications.

Self-testing kits are also one of the significant factors contributing to market growth as the waiting lists in the medical facilities are increasing due to the increase in the population count. Hence, it is easy, and the best way to test the glucose levels at home, it saves time and energy. 

Market Segments of the Blood Glucose Monitoring Market

There are three segments to the blood glucose monitoring market:

By product type: Continuous glucose monitoring devices, invasive monitoring devices, flash glucose monitoring devices and others are some types of devices. Continuous glucose monitoring devices market is expected to face maximum adoption and growth due to increased demand for non-invasive methods.

By application: These monitoring devices are used for detection of type 1 diabetes type 2 diabetes and gestational diabetes. Type 2 diabetes will be the most significant area for its application due to an increase in related patients.

By End-Users: Hospitals, clinics, diagnostic centres, and home care facilities are some end-users of glucose monitoring devices. Home care devices are projected to be the dominant player among all of the above.

Regional Overview

The global blood glucose monitoring devices market is observed based on four markets in America, Europe, Asia Pacific and The Middle East & Africa.

The American region is the biggest market presently due to unhealthy lifestyles and increased obesity patients. Also, already well-established healthcare facilities, rapidly growing research & development programs and increasing investments are adding to the market share and progress. Europe is in second place because of the need for better healthcare measures and rapid increase in patients. Research and development are playing an important role and resulting in increased investments.

The Asia Pacific is in the third position and will face the fastest growth during the projected period. Demand for new treatment procedures, urbanisation, improved healthcare facilities is fuelling and continue the same in the future.

The Middle East & African regions hold the lowest market share and growth speeds. 

Recent Industry News

Increased preference for non-invasive techniques calls for newer inventions. Asia pacific region will emerge as the fastest-growing market. Introduction of latest technologies and inventions will boost the market growth and individual company’s growth.

Read more @ https://www.marketresearchfuture.com/reports/blood-glucose-monitoring-market-557 

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Analysis Report: Biopharmaceuticals Market Size, share, Trends, Comprehensive Growth by Top Leaders

 Biopharmaceuticals Market Overview

International Biopharmaceuticals Market is anticipated to reach USD 394,998.5 Million by the forecasted year of 2025. This feat is expected to happen at a CAGR of 8.99%. With the growing level of investments and interest from the leading pharmaceutical companies is said to be the prime reasons behind the growth of the market. Not just in biotechnology, the level of investment has grown in biopharmaceutical research and development domain as well, opening the scope for the market boost.  

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It’s not just that the investment level has grown; the level of acceptance of biopharmaceuticals has been quite encouraging as well. It’s the greater ability to treat the diseases that used to remain untreated in modern times that has enhanced the scope of the market. Advancing technology is also a prime reason behind the same. It is evident that the level of geriatric population has increased significantly in recent times, widening the market scope immensely. It is here to note that one in every six people in the world is more than 65 years.

As evident, the technological advancement in this segment has grown significantly. The level of regulations from local government is much relaxed as well in modern times than ever. Promotional aspects look encouraging in this segment, promising a lot about market growth. People are being convinced that the level of side-effects associated with biopharmaceuticals has gone down to a great extent, making things much reliable than ever.      

Biopharmaceuticals Market Segmentation

The global biopharmaceutical market can be segmented on the basis of product type, in terms of application, and on the basis of region. On the basis of product type, the global biopharmaceutical market can be further segmented into monoclonal antibodies, Recombinant Growth Factors, Purified Proteins, Recombinant Proteins, Recombinant Hormones, Vaccines, Synthetic Immunomodulators, and others. In terms of application, the market can be further segmented into Oncology, Inflammatory and Infectious Diseases, Autoimmune Disorders, Metabolic Disorders, Hormonal Disorders, Disease Prevention, Cardiovascular Diseases, Neurological Diseases, and others. On the basis of region, the market is segmented into America, Europe, Asia Pacific, Middle East, and Africa.        

Biopharmaceuticals Market Regional Analysis

On the basis of region, the global biopharmaceutical market is segmented into America, Europe, Asia Pacific, Middle East, and Africa. America is indeed the leading market among all due to a higher rate of occurrence of cancer in this part of the world. Around 10 million people have died due to cancer by 2019. Europe comes next to America powered by its growing geriatric population and well-established infrastructure for health domain. The rate of occurrence of neurological disease is also high in Europe. The Asia Pacific is one of the significantly growing markets due to growing population in nations like India and China. The Middle East and Africa show equally incredible promise as well.

Biopharmaceuticals Market Key Players

  • Pfizer, Inc. (US)

  • Amgen Inc. (US)

  • Eli Lilly and Company (US)

  • Hoffmann-La Roche Ltd (Switzerland)

  • Johnson & Johnson (US)

  • Gilead Sciences, Inc. (US)

  • AstraZeneca (UK)

  • Abbvie Inc. (US)

  • Sanofi (France)

  • Bristol-Myers Squibb Company (US)

  • Sandoz International GmbH (Germany)

  • Novo Nordisk A/S (Denmark)

  • GlaxoSmithKline PLC (UK)

  • Merck KGaA (Germany)

  • Biocon (India)


Industry News

3rd Watch News publishes a report about the market scenario of global biopharmaceutical market. It analyses all the factors associated with the growth of the market. Also, the report identifies the major parts where the market growth can be the most significant. The report predicts the overall growth rate at which the market is expected to expand at these parts.      

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Wednesday, 9 September 2020

Apoptosis Assays Market 2019 is Projected to Exhibit a CAGR of 9.4% during the Forecast period 2024 Consumer research, Report Covering Major Key Points

Apoptosis assay, or programmed cell death, is a growth limiting mechanism   which is devised in case of extracellular signals because of DNA damage. In apoptosis assay, cells are genetically ablated. Apoptosis assays include cell shrinkage, chromosome condensation, membrane blebbing, DNA laddering, nuclear fragmentation, and others. Market Research Future (MRFR) has published an in-depth report on the global apoptosis assay market and has predicted a CAGR of 9.4% over the forecast period of 2018-2023. The market stood at USD 2.99Bn in 2017. 

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Aggressive efforts in cell-based research studies is a key factor driving the apoptosis assay market. The governments of multiple countries, as well as, various private entities are outlaying massive amounts on cell-based research studies. For instance, in 2017, the National Institutes of Health (NIH) invested USD 1.65 Bn for stem cell research. Such investments have been pouring in recently, given the surge in the incidence rate of chronic diseases across the globe. Autoimmune diseases, neurodegenerative diseases, and oncological disorders are spreading at an alarming rate. Such towering occurrences of such disorders have evoked intensive R&D activities for drug development, which is fueling the growth of the apoptosis assay market. In contrast, the apoptosis assays require hefty investments, which can trim the growth of the market over the forecast period. 

Segmentation

The apoptosis assays market has been segmented based on product, detection technology, application, and end user.

By product, the apoptosis assays market has been segmented into kits, reagents, instruments, and others. The kits segment dominated the market in 2017.  

By detection technology, the apoptosis assays market has been segmented into flow cytometry, fluorescence microscopy, western blot assessment, gel electrophoresis, and others. The flow cytometry segment led the market in 2017.

By application, the apoptosis assays market has been segmented into drug discovery and development, stem cell research, and others. Application-wise, the drug discovery and development segment is leading the market while the stem cell research segment is expected to be the fastest growing segment over the forecast period. 

 

By end user, the apoptosis assays market has been segmented into pharmaceutical and biological companies, research institutes, and others. The pharmaceutical and biological companies segment is leading the market while the research institute segment is likely to be the fastest growing segment over the forecast period. 

 regional Analysis

Region-wise, the apoptosis assay market has been segmented into the Americas, the Middle East & Africa (MEA), Europe, and Asia Pacific (APAC). 

The Americas is dominating the global apoptosis assay market on account of the concentration of major market players in the region and increasing R&D expenditure. The prevalence of various chronic diseases is also considerably high in the region which has led to extensive R&D efforts. The US is a key contributor to the Americas market. 

Europe accounts for the second largest share of the global apoptosis asay market. The growth of the market can be attributed to the expanding pharmaceutical and biotech industry in the region. In addition, government support has facilitated rigorous R&D activities in the field of cell-based research, which is boosting the growth of the market. Other factors supporting the growth of the market include heightened investment in R&D by market players, the presence of a well=established market players, and increasing awareness regarding targeted therapy. 

The APAC apoptosis assay market is likely to exhibit the highest CAGR over the forecast period. Increasing R&D expenditure, surging prevalence of chronic diseases, and rising government support is driving the market in APAC.  

Competitive Landscape

GeneCopoeia, Inc. (US), Danaher Corporation (US), GE Healthcare (US), Becton, Dickinson and Company (US), Bio-Rad Laboratories (US), Geno Technology (US), Thermo Fisher Scientific (US), Promega Corporation (US) , Abcom plc, Merck KGaA (Germany), and Sartorius AG (Germany) are the key players in the apoptosis assays market.

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Top Leading Companies Focus on Adhesion Barrier Market Size, Trends, Analysis and Regional Growth

  

Adhesion Barrier Market Highlights

As per Market Research Future (MRFR) analysis, the global adhesion barrier market is expected to reach USD 928.78 million with a CAGR of 7.32% from 2019 to 2025 (forecast period).

Adhesion barrier is a medical implant used in patients with abdominal or pelvic laparotomy as an alternative to the removal of postoperative adhesions between the abdominal wall and the underlying viscera.

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Market Dynamics

The adhesion barrier market is expected to expand at a steady growth rate. Significant factors impacting the market growth include rising surgical procedures for small bowel obstruction, infertility and chronic pelvic pain, and cost-effective adhesion prevention. The majority of laparoscopic procedures contribute to adhesions. It is estimated that more than 400,000 laparotomies are conducted annually in the United States for small bowel obstruction. In the United States, obstetricians-gynecologists have been shown to perform two of the most common surgical procedures, involving cesarean delivery and abdominal hysterectomy, which is associated with the risk of developing pelvic adhesions. The study found that adhesions occur in approximately 97% of abdominal interventions that cause chronic pain, infertility, and intestinal obstruction. Moreover, cost-effective prevention of adhesions is also driving the growth of the market. For open surgery, the adhesion barrier lowers the cost of surgery relative to no adhesion barrier, i.e., USD 4.376 versus USD 4.482. A four-year study was conducted in the US, and it was found that the average cost of colorectal surgery had been reduced to USD 106, from USD 4.482 without an adhesion barrier to USD 4.376 with an adhesion barrier.

However, the risk of the use of the adhesion barrier in patients with a history of hypersensitivity and the choice of adhesion barriers among surgeons may hinder the growth of the market.

 

Adhesion Barrier Market Segmentation

The global market for adhesion barrier has been segmented into product, formulation, severity, and application. 

By product, the global market for adhesion barrier has been segmented into synthetic adhesion barriers and natural adhesion barriers. The synthetic adhesion barriers are further divided into hyaluronic acid, regenerated cellulose, and polyethylene glycol. Synthetic adhesion barriers accounted for the largest market share due to several advantages over natural adhesion barriers, including high biocompatibility, bioresorbable property, and cost-effectiveness of these products. The natural adhesion barriers are further segmented into collagen & protein, fibrin.

By formulation, the global adhesion barrier has been segmented into film, gel, and liquid. Film based adhesion barriers are projected to hold the largest market share due to better handling characteristics and proven positive results. Leading manufacturers for these products are J&J, Sanofi, and others. Gel-based adhesion barriers are composed of polyethylene oxide and sodium carboxymethylcellulose, with protective activity. Liquid-based adhesion barriers are aimed to create a site-specific barrier on a target

By severity, the global market for adhesion barrier has been segmented into mild adhesion and severe adhesion. Mild adhesion was the largest market share. According to a study of 122 patients, only three patients were found to have switched from mild to severe adhesion. Example of mild adhesion includes filmy and avascular. Severe adhesion is expected to hold the least market share. Example of severe adhesion includes organized, cohesive, vascular, and dense

By application, the global market for adhesion barrier has been described by gynecological surgeries. Gynecological surgeries are projected to have the largest market share due to a large number of gynecological procedures, and many women are likely to experience post-surgical adhesions. It is estimated that 90 % of patients undergo main abdominal surgery and that between 55% and 100% of females undergo pelvic surgery develop adhesions.

 

Adhesion Barrier Market  Regional Analysis

Regionally, the global adhesion barrier market has been segmented into the Americas, Europe, the and Asia Pacific.

The Americas led the adhesion barrier market in 2019 and is expected to continue to dominate the market throughout the forecast period. This is due to the existence of a large number of medical device firms, a rise in research and development, an increase in laparoscopy procedures, and a large number of patients. More than 400,000 laparotomies are conducted annually in the United States alone for small bowel obstruction.

Europe is projected to hold the second-largest share due to increased use of advanced technologies and increased product development by existing manufacturers.

The Asia Pacific is projected to rise at the highest rate of growth during the study period. This is due to widely populated countries such as China, India, Indonesia, Pakistan, and Bangladesh, growing gynecological procedures, and increasing government initiatives to raise awareness of women's related diseases.

 

Adhesion Barrier Market  Studied by Top Key Players 

Some of the leading participants in the global adhesion barrier are Johnson & Johnson, Atrium Medical Corporation (A Part of Getinge Group), Betatech Medical, R. Bard, FzioMed, Innocoll Holdings, Anika Therapeutics, Integra LifeSciences Holdings Corporation, Baxter International, MAST Biosurgery, Normedi Nordic., Sanofi.

 

Industry News

In December 2019, Baxter International announced that it would acquire Sanofi's surgical products unit Seprafilm and related assets for USD 350 million in cash. The deal is scheduled to close in the first quarter of 2020.

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Global Dry Mouth Relief Market: Information by Type (Spray, Mouthwash, Gel, Lozenges), Distribution Channel (Pharmacies, E-Commerce, Supermarket) and Region (Americas, Europe, Asia-Pacific, Middle East & Africa) - Forecast till 2026: https://www.marketresearchfuture.com/reports/dry-mouth-relief-market-9581 

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